Bulletin of the Chemical Society of Ethiopia | |
Synthesis of new nano Schiff base complexes: X-ray crystallography, thermal, electrochemical and anticancer studies of nano uranyl Schiff base complexes | |
关键词: Uranyl Schiff base complex; Anticancer activities; Thermal studies; Electrochemistry; X-ray crystallography; | |
DOI : https://dx.doi.org/10.4314/bcse.v32i1.8 | |
来源: DOAJ |
【 摘 要 】
This study presents synthesis and characterization of new nano uranyl Schiff base complexes. Electrochemistry of these complexes showed a quasireversible redox reaction without any successive reactions. Furthermore, X-ray crystallography exhibited that beside the coordination of tetradentate Schiff base, one solvent molecule (dimethylformamide) was also coordinated. According to Coats-Redfern plots the kinetics of thermal decomposition of the studied complexes was first-order in all stages. Anticancer activities of the uranyl Schiff base complexes against cancer cell lines (Jurkat) was studied and determined by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazoliumbromide) assay. The results demonstrated that the complexes with aliphatic bridging units showed less anticancer activities than those having the aromatic units.
【 授权许可】
Unknown