Cyclic Biamperometry

Electrochemistry;Cyclic voltammetry;Electroanalytical Chemistry;Bioanalytical Chemistry;Chemistry

Rahimi, Mohammad Mehdi

University of Waterloo

关键词: Electrochemistry;    Cyclic voltammetry;    Electroanalytical Chemistry;    Bioanalytical Chemistry;    Chemistry;   

Others  :  https://uwspace.uwaterloo.ca/bitstream/10012/4555/1/Rahimi_M_M_MasterThesis.pdf

瑞士|英语

来源: UWSPACE Waterloo Institutional Repository

【 摘 要 】

In this thesis, cyclic biamperometry (CB) as a new method in electrochemistry,has been introduced and investigated. The hallmark of this method is the absenceof a reference electrode which potentially allows simplification and miniaturizationof the measurement apparatus. Similarities anddifferences of this method andcyclic voltammetry (CV) have been studied and it was shown that under conditionsof using standard electrodes, CB has a better sensitivity and a lower detectionlimit than CV. A new equivalent circuit model for the cell has been proposed andparametersaffecting the sensitivity of CB, such as keeping the concentration ofone redox species in excess and having a larger W2 electrode, have been described.The redox cycling effect in biamperometric systems has been investigated and itis shown that improvements of at least two orders of magnitude in sensitivity canbe achieved by using interdigitated electrodes (IDEs). In addition, an examplefor applications of this method, including biamperometric dead-stop titration of1-naphthol with ferricyanide, has been presented and possiblefields in which CB canbe incorporated (e.g. monitoring the activity of alkaline phosphatase) have beenillustrated. Finally, a few suggestions for future studies and further improvementshave been outlined.