Nauclea officinalis: A Chinese medicinal herb with phytochemical, biological, and pharmacological effects

Chinese Medicine

Review

Li Li¹  Peipei Lu¹  Lin Lin¹  Bin Liu¹  Qi Geng¹  Lan Yan¹  Zhiwen Cao¹  Cheng Lu¹ 

[1]Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Dongcheng District, 100700, Beijing, China

关键词: Nauclea officinalis;    Phytochemistry;    Biological activity;    Pharmacological effect;   

DOI  :  10.1186/s13020-022-00691-8

 received in 2022-09-28, accepted in 2022-11-22,  发布年份 2022

来源: Springer

【 摘 要 】

Nauclea officinalis(N. officinalis), a medicinal plant of the genus Nauclea in the family Rubiaceae, is used in the treatment of fever, pneumonia, pharyngolaryngitis, and enteritis in China. Extracts of N. officinalis include alkaloids, phenolic acids, pentacyclic triterpenoids, and flavonoids, which exert all kinds of pharmacological effects, for instance anti-inflammatory, anti-tumor, antibacterial, and antiviral and therefore show good effectiveness. To gain a comprehensive and deep understanding, the medicinal chemistry and chemical biology of N. officinalis are summarized in this review to provide a theoretical basis. The pharmacological effects were reviewed to provide evidence or insights into potential opportunities for further studies and medicinal exploitation of N. officinalis.

【 授权许可】

CC BY   
© The Author(s) 2022

【 图 表 】

12982_2022_119_Article_IEq92.gif

12982_2022_119_Article_IEq90.gif

Fig. 1

12982_2022_119_Article_IEq88.gif

12982_2022_119_Article_IEq87.gif

12982_2022_119_Article_IEq86.gif

12982_2022_119_Article_IEq231.gif

12982_2022_119_Article_IEq230.gif

12982_2022_119_Article_IEq229.gif

Fig. 1

12982_2022_119_Article_IEq226.gif

12982_2022_119_Article_IEq225.gif

12982_2022_119_Article_IEq223.gif

Fig. 1

Fig. 10

Fig. 4

Fig. 3

Fig. 2

Fig. 2

Fig. 6

Fig. 5

Fig. 1

Fig. 4

Fig. 4

Fig. 2

12982_2022_119_Article_IEq219.gif

12982_2022_119_Article_IEq218.gif

12982_2022_119_Article_IEq217.gif

12982_2022_119_Article_IEq216.gif

12982_2022_119_Article_IEq214.gif

Fig. 3

12982_2022_119_Article_IEq212.gif

Fig. 2

12982_2022_119_Article_IEq210.gif

Fig. 1

12982_2022_119_Article_IEq69.gif

12982_2022_119_Article_IEq68.gif

12982_2022_119_Article_IEq205.gif

12982_2022_119_Article_IEq195.gif