Myocardial arterial spin labeling

Journal of Cardiovascular Magnetic Resonance

Review

Frank Kober¹  Thomas Troalen¹  Terrence Jao²  Krishna S. Nayak³ 

[1] Aix-Marseille Université, CNRS CRMBM UMR 7339, Centre de Résonance Magnétique Biologique et Médicale, Marseille, France;Department of Biomedical Engineering, University of Southern California, Los Angeles, California, USA;Department of Biomedical Engineering, University of Southern California, Los Angeles, California, USA;Ming Hsieh Department of Electrical Engineering, University of Southern California, Los Angeles, California, USA;

关键词: Myocardial perfusion;    Arterial spin labeling;    Cardiovascular magnetic resonance;    Ischemic heart disease;   

DOI  :  10.1186/s12968-016-0235-4

 received in 2015-12-22, accepted in 2016-03-22,  发布年份 2016

来源: Springer

【 摘 要 】

Arterial spin labeling (ASL) is a cardiovascular magnetic resonance (CMR) technique for mapping regional myocardial blood flow. It does not require any contrast agents, is compatible with stress testing, and can be performed repeatedly or even continuously. ASL-CMR has been performed with great success in small-animals, but sensitivity to date has been poor in large animals and humans and remains an active area of research. This review paper summarizes the development of ASL-CMR techniques, current state-of-the-art imaging methods, the latest findings from pre-clinical and clinical studies, and future directions. We also explain how successful developments in brain ASL and small-animal ASL-CMR have helped to inform developments in large animal and human ASL-CMR.

【 授权许可】

CC BY   
© Kober et al. 2016