Parity is associated with long-term differences in DNA methylation at genes related to neural plasticity in multiple sclerosis

Clinical Epigenetics

Research

Mark Slee¹  Trevor Kilpatrick²  Jim Stankovich³  Maria Pia Campagna³  Wei Z. Yeh⁴  Helmut Butzkueven⁴  Vilija G. Jokubaitis⁵  Rodney A. Lea⁶  Jeannette Lechner-Scott⁷  Vicki E. Maltby⁷  Alexandre Xavier⁸  Rodney J. Scott⁸ 

[1] College of Medicine and Public Health, Flinders University, Adelaide, Australia;Department of Medicine, University of Melbourne, Melbourne, VIC, Australia;Department of Neurology, Royal Melbourne Hospital, Melbourne, VIC, Australia;Department of Neuroscience, Monash University, Melbourne, VIC, Australia;Department of Neuroscience, Monash University, Melbourne, VIC, Australia;Neurology Department, Alfred Health, Melbourne, VIC, Australia;Department of Neuroscience, Monash University, Melbourne, VIC, Australia;Neurology Department, Alfred Health, Melbourne, VIC, Australia;Department of Medicine, University of Melbourne, Melbourne, VIC, Australia;Department of Neurology, Royal Melbourne Hospital, Melbourne, VIC, Australia;Hunter Medical Research Institute, University of Newcastle, Newcastle, NSW, Australia;Queensland University of Technology, Brisbane, QLD, Australia;Hunter Medical Research Institute, University of Newcastle, Newcastle, NSW, Australia;School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia;Neurology Department, John Hunter Hospital, Hunter New England, Newcastle, NSW, Australia;School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia;Hunter Medical Research Institute, University of Newcastle, Newcastle, NSW, Australia;

关键词: Pregnancy;    Birth;    Epigenetics;    Neurodegeneration;    Neuroplasticity;   

DOI  :  10.1186/s13148-023-01438-4

 received in 2022-04-11, accepted in 2023-02-05,  发布年份 2023

来源: Springer

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

Fig. 5

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