Coatings on mammalian cells: interfacing cells with their environment

Journal of Biological Engineering

Kara A. Davis¹  Brad J. Berron¹  Pei-Jung Wu¹  Anuhya Gottipati¹  Calvin F. Cahall¹  Cong Li¹ 

[1] Chemical and Materials Engineering, University of Kentucky;

关键词: Mammalian cells;    Coatings;    Polymers;    Cell therapy;    Cellular coatings;   

DOI  :  10.1186/s13036-018-0131-6

来源: DOAJ

【 摘 要 】

Abstract The research community is intent on harnessing increasingly complex biological building blocks. At present, cells represent a highly functional component for integration into higher order systems. In this review, we discuss the current application space for cellular coating technologies and emphasize the relationship between the target application and coating design. We also discuss how the cell and the coating interact in common analytical techniques, and where caution must be exercised in the interpretation of results. Finally, we look ahead at emerging application areas that are ideal for innovation in cellular coatings. In all, cellular coatings leverage the machinery unique to specific cell types, and the opportunities derived from these hybrid assemblies have yet to be fully realized.

【 授权许可】

Unknown