Effect of Various Exercise Regimens on Selected Exercise-Induced Cytokines in Healthy People

International Journal of Environmental Research and Public Health

卷:18

Michał Pytka¹  Przemysław Guzik¹  Remigiusz Domin²  Marek Ruchała²  Ariadna Zybek-Kocik²  Daniela Dadej² 

[1] Department of Cardiology-Intensive Therapy, Poznan University of Medical Sciences, 60-355 Poznań, Poland;

[2] Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, 60-355 Poznań, Poland;

关键词: myokines;    hepatokines;    exercise;    myostatin;    follistatin;    brain-derived neurotrophic factor;   

DOI  :  10.3390/ijerph18031261

来源: DOAJ

【 摘 要 】

Different forms of physical activity—endurance, resistance or dynamic power—stimulate cytokine release from various tissues to the bloodstream. Receptors for exercise-induced cytokines are present in muscle tissue, adipose tissue, liver, brain, bones, cardiovascular system, immune system, pancreas, and skin. They have autocrine, paracrine and endocrine activities. Many of them regulate the myocyte growth and differentiation necessary for muscle hypertrophy and myogenesis. They also modify energy homeostasis, lipid, carbohydrate, and protein metabolism, regulate inflammation and exchange information (crosstalk) between remote organs. So far, interleukin 6 and irisin have been the best studied exercise-induced cytokines. However, many more can be grouped into myokines, hepatokines and adipomyokines. This review focuses on the less known exercise-induced cytokines such as myostatin, follistatin, decorin, brain-derived neurotrophic factor, fibroblast growth factor 21 and interleukin 15, and their relation to various forms of exercise, i.e., acute vs. chronic, regular training in healthy people.

【 授权许可】

Unknown