Sex‐specific accelerated decay in time/activity‐dependent plasticity and associative memory in an animal model of Alzheimer's disease

Aging Cell

Maria Vazquez Pavon¹  Yee Song Chong¹  Riya Prasad Abraham¹  Sreedharan Sajikumar²  Jessica Ruth Gaunt³  Vibhavari Aysha Bansal³  Sheeja Navakkode⁴  Toh Hean Ch'ng⁵ 

[1] Department of Physiology, National University of Singapore, Singapore, Singapore;Department of Physiology, National University of Singapore, Singapore, Singapore;Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore;Life Sciences Institute Neurobiology Programme, National University of Singapore, Singapore, Singapore;Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore;Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore;Department of Physiology, National University of Singapore, Singapore, Singapore;Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore;School of Biological Science, Nanyang Technological University, Singapore, Singapore;

关键词: Alzheimer's disease;    behavioural tagging;    LTP;    sexual dimorphism;    STDP;    synaptic plasticity;    synaptic tagging and capture;    transcriptome profiling;   

DOI  :  10.1111/acel.13502

来源: Wiley

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