Long-term exposure to high-concentration silver nanoparticles induced toxicity, fatality, bioaccumulation, and histological alteration in fish (Cyprinus carpio)

Environmental Sciences Europe

Kalim Ullah¹  Ikram Khan²  Qi Zhang³  Mian Adnan Kakakhel⁴  Wanfu Wang⁵  Fasi Wu⁵  Wasim Sajjad⁶ 

[1] Department of Zoology, Kohat University of Science and Technology, Kohat, Khyber Pakhtunkhwa, Pakistan;Key Laboratory of Oral Disease of Gansu Province, School of Stomatology, Northwest University for Nationalities, 730000, Lanzhou, People’s Republic of China;MOE Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, 730000, Lanzhou, People’s Republic of China;MOE Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, 730000, Lanzhou, People’s Republic of China;Department of Zoology, Kohat University of Science and Technology, Kohat, Khyber Pakhtunkhwa, Pakistan;MOE Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, 730000, Lanzhou, People’s Republic of China;National Research Center for Conservation of Ancient Wall Paintings and Earthen Sites, Department of Conservation Research, Dunhuang Academy, 736200, Dunhuang, Gansu, People’s Republic of China;State Key Laboratory of Cryospheric Science, Northwest Institute of Eco‐Environment and Resources, Chinese Academy of Sciences, 730000, Lanzhou, People’s Republic of China;

关键词: Novel Silver nanoparticles;    Ecotoxicity;    Bioaccumulation;    Histopathological alterations;    Enzymatic stress;   

DOI  :  10.1186/s12302-021-00453-7

来源: Springer

【 摘 要 】

BackgroundCurrently, nanotechnology and nanoparticles have quickly emerged and have gained the attention of scientists due to their massive applications in environmental sectors. However, these environmental applications of silver nanoparticles potentially cause serious effects on terrestrial and aquatic organisms. In the current study, freshwater fish C. carpio were exposed to blood-mediated silver nanoparticles for toxicity, mortality, bioaccumulation, and histological alterations. Silver nanoparticles were fabricated using animal blood serum and their toxic effect was studied against common carp fish at different concentrations levels (0.03, 0.06, and 0.09 mg/L).ResultsThe findings have revealed a little influence of blood-induced silver nanoparticles on fish behavior at the highest concentration (0.09 mg/L). However, bioaccumulation of blood-mediated silver nanoparticles was reported in different organs of fish. Maximum bioaccumulation of silver nanoparticles was reported in the liver, followed by the intestine, gills, and muscles. Furthermore, the findings have shown that the bioaccumulation of silver nanoparticles led to histopathological alterations; including damaged structure of gill tissue and have caused necrosis. It is summarized that histopathological alteration in gill and intestine mostly occurred by the highest concentration of blood-induced silver nanoparticles (0.09 mg/L).ConclusionThis study provides evidence of the silver nanoparticles influence on aquatic life; however, further systematic studies are crucial to access the effects of AgNPs on aquatic life.

【 授权许可】

CC BY