Effect of Cefotaxime on the CAT Activities and GSH Contents of Zebrafish

2018 2nd International Workshop on Renewable Energy and Development

能源学;经济学

Wang, Yaxue^1 ; Shen, Hong-Yan^1

College of Environmental Science and Engineering, Pharmaceutical Molecular Chemistry Laboratory of Hebei Province, Hebei University of Science and Technology, Shijiazhuang, China^1

关键词: Cefotaxime;    Ecotoxicity;    Exposed to;    Glutathiones;    Indoor exposure;    Muscle tissues;    Zebrafish;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/153/6/062071/pdf
DOI  :  10.1088/1755-1315/153/6/062071

来源: IOP

【 摘 要 】

In order to define eco-toxicity effect of cefotaxime on zebrafish, the indoor exposure method was used to study the impact of cefotaxime on zebrafish. In this study, zebrafish was exposed to cefotaxime of 1mg/L, 5mg/L, 25mg/L and 125mg/L for 15 days to study the effect of Catalase (CAT) activities and Glutathione (GSH) contents. According to the experimental data, the CAT activities and GSH contents in zebrafish muscle tissue had changed significantly during the period of exposure. The experimental results show that the activities of CAT in four concentration groups were significantly inhibited (P