The Recent Status of Multidrug- and Extensively Drug-Resistant Tuberculosis in Korea.

Tuberculosis and Respiratory Diseases

article

Kim, Sun Young¹  Kim, Hee Jin²  Kim, Chang Ki²  Yoon, Hye Ryung³  Bae, Hye Gyung⁴  Lee, Sun Hwa⁵  Sung, Nackmoon⁶  Kim, Dae Yeon⁷  Lee, Gang Young⁸  Cho, Young Soo⁸  Lee, Sang Do¹  Kim, Woo Sung¹  Kim, Dong Soon¹  Shim, Tae Sun¹ 

[1] Division of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine;Division of Korean Institute of Tuberculosis;Division of Seoul Medical Science Institute;Division of Green Cross Reference Laboratory;Division of Neodin Medical Institute;Division of National Masan Hospital;Division of National Mokpo Hospital;Division of Seobuk Hospital

关键词: Tuberculosis;    Multidrug-Resistant;    Extensively Drug-Resistant Tuberculosis;    Microbial Sensitivity Tests;    Korea;   

DOI  :  10.4046/trd.2010.68.3.146

学科分类：医学（综合）

来源: The Korean Academy of Tuberculosis and Respiratory Diseases

【 摘 要 】

BACKGROUND The increasing incidence of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) has become a serious worldwide problem. However, there is insufficient data regarding the current status of MDR-TB and XDR-TB in Korea. This study examined the recent status of MDR- and XDR-TB using the data from 7 laboratories, in which almost all drug susceptibility tests (DST) for Mycobacterium tuberculosis were performed. METHODS: The patients' identification data and DST results were collected from all 7 laboratories from 2001 to 2006 and the number of patients with MDR-TB and XDR-TB were calculated. RESULTS: The number of DSTs was 140,638 for 6 years with an increasing incidence each year (p<0.001). The number of DST with MDR results was 18,510 and personal identifying information was obtained in 16,640 (89.9%) tests. The number of MDR-TB patients from 2001 to 2006 was 2,329, 2,496, 2,374, 2,300, 2,354, and 2,178, respectively, when counting the duplications in a year as one patient. The number of MDR-TB patients when counting the duplications in 6 years as one patient was 2,281, 1,977, 1,620, 1,446, 1,512, and 1,373, respectively. When the same method was adopted, the number of XDR-TB patients was 191, 238, 282, 260, 272, and 264, respectively, and 189, 150, 130, 90, 122, and 110 patients, respectively. CONCLUSION: Despite the national efforts to control TB, there are still a large number of MDR- and XDR-TB patients in Korea.

【 授权许可】

CC BY-NC