Identification of Mycobacterium tuberculosis Bacteria with TB Antigen MPT64 Rapid Test Against Patients with Suspect Pulmonary Tuberculosis in Lubuk Alung Pulmonary Hospital, Padang Pariaman

12th Congress of Indonesian Soc. for Biochemistry and Molecular Biology in Conjunction With The 2nd Int. Conf. "Collaboration Seminar of Chemistry and Industry

生物科学;化学

Bahar, E.^1 ; Putra, A.E.^1

Microbiology Department, Faculty of Medicine, Andalas University, Jl. Perintitis Kemerdekaan No. 94, Padang

25127, Indonesia^1

关键词: Early diagnosis;    Infectious disease;    M tuberculosis;    MPT64;    Mycobacterium tuberculosis;    Prevention and controls;    Pulmonary tuberculosis;    Tuberculosis;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/217/1/012061/pdf
DOI  :  10.1088/1755-1315/217/1/012061

学科分类：生物科学（综合）

来源: IOP

【 摘 要 】

Tuberculosis (TB) is old disease which is still the most killer among infectious diseases and the world is still not free from TB. According to the WHO 2017 report there are an estimated 1,020,000 cases in Indonesia, but 420,000 have just been reported. The extent of TB problems requires prevention and control as soon as possible for early diagnosis. AFB methods, culture and PCR diagnosis of TB have limitations. Culture on Lowenstein Jensen media is a standard diagnosis of TB gold, but growing colonies need identification of M tuberculosis bacteria. The aim of the study was to identify M tuberculosis bacteria using a rapid test (MPT64 Rapid SD TB Ag). As many as 100 samples of patients suspected of TB obtained 48 (48%) positive cultures. From 48 positive cultures with rapid test, 46 (95.8%) M tuberculosis bacteria and 2 (4.2%) non M tuberculosis were obtained. It can be concluded that identification with the rapid test (SD TB Ag MPT64) is M tuberculosis bacteria.