Severe falciparum malaria with acute kidney injury: a case report

3rd Annual Applied Science and Engineering Conference

工业技术;自然科学

Kurnianingrum, N.M.A.^1 ; Ayu, N.P.^1

Siloam Nusa Dua Hospital, Bali, Indonesia^1

关键词: Clinical manifestation;    Diagnostic tests;    Early diagnosis;    Falciparum malaria;    Mortality rate;    P. falciparum;    Renal functions;    Thrombocytopenia;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/434/1/012316/pdf
DOI  :  10.1088/1757-899X/434/1/012316

来源: IOP

【 摘 要 】

Malaria is still a health problem in the world, particularly in Indonesia with high morbidity and mortality rate. Since infections with P. falciparum generally result in serious disease, their identification is important. We reported a case of kidney injury associated with malaria in a 36-year-old Australian who resided recently in Sumba Barat, Nusa Tenggara Timur, Indonesia who had been treated as malaria without knowing the species of plasmodium with oral dihydroartemisinine-piperaquine and primaquine. Clinical manifestation included jaundiced, thrombocytopenia, elevated creatinine and urea. The rapid diagnostic test for malaria and microscopic examination of blood smears were positive for P. falciparum. On the basis of this, the patient was diagnosed as having acute kidney injury as a complication of severe malaria. The patient was treated for malaria with intravenous artesunate for 3 days, then followed by oral treatment of dihydroartemisinine-piperaquine. He also had six rounds of dialysis after which he partially recovered renal function. This outcome is not always the rule. Prognosis depends much on early diagnosis and appropriate supportive treatment.