Diagnostic approach in leptospirosis patients

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Sembiring, E.^1

Division of Infectious and Tropical Diseases, Department of Internal Medicine, Universitas Sumatera Utara, Adam Malik Hospital, Medan, Indonesia^1

关键词: Clinical manifestation;    Contaminated water;    Diagnostic approach;    Domestic animals;    Indirect contact;    Pathogenic species;    Subtropical regions;    Zoonotic disease;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012089/pdf
DOI  :  10.1088/1755-1315/125/1/012089

来源: IOP

【 摘 要 】

Leptospirosis is as a worldwide zoonotic disease, spread by pathogenic species of the bacterial genus Leptospira that occurs most commonly in tropical and subtropical regions which are one of endemic diseases in some places in Indonesia. The leptospira serovars are naturally carried in the renal tubules of rodents, wild and domestic animals. Human can be infected either through direct contact with urine of infected animals or indirect contact through with contaminated water and soil. Clinical manifestation is highly variable. The most cases are with a mild flu-like illness which may mimic many other diseases. Weil's disease is the name given to severe illness and is characterized by a severe febrile illness with bleeding, jaundice and renal failure with high mortality rate. Leptospirosis has been frequently underdiagnosed and underreported. The diagnosis of leptospirosis is difficult to confirm and laboratory test is rarely available even in endemic areas.