Histological analysis of low-intensity laser therapy effects in peripheral nerve regeneration in Wistar rats

Acta Cirurgica Brasileira

Cibele Nazaré Da Silva Câmara²  Marcus Vinicius Henriques Brito¹  Edvaldo Lima Silveira¹  Diego Sá Guimarães Da Silva¹  Vivian Roberta Ferreira Simões¹  Roberto Waldesmand Farias Pontes¹ 

[1] ,UNAMA Department of Physiotherapy Belem PA ,Brazil

关键词: Laser Therapy;    Low-Level;    Nerve Regeneration;    Rats;    Wistar;    Terapia a Laser de Baixa Intensidade;    Regeneração Nervosa;    Ratos Wistar;   

DOI  :  10.1590/S0102-86502011000100004

来源: SciELO

【 摘 要 】

Purpose: Analyze the influence of low-intensity laser therapy in the sciatic nerve regeneration of rats submitted to controlled crush through histological analysis. Methods: Were used 20 Wistar rats, to analyze the influence of low-intensity laser therapy in the sciatic nerve regeneration, where the injury of the type axonotmesis was induced by a haemostatic clamp Crile (2nd level of the rack). The animals were randomly distributed in 2 groups. Control group (CG n = 10) and Laser group (LG n = 10). These were subdivided in 2 subgroups each, according to the euthanasia period: (CG14 _ n = 5 and CG21 _ n = 5) and (LG14 _ n = 5 and LG21 _ n = 5). At the end of treatment, the samples were removed and prepared for histological analysis, where were analyzed and quantified the following findings: Schwann cells, myelinic axons with large diameter and neurons. Results: In the groups submitted to low-intensity laser therapy, were observed an increase in the number of all analyzed aspects with significance level. Conclusion: The irradiation with low intensity laser (904nm) influenced positively the regeneration of the sciatic nerve in Wistar rats after being injured by crush (axonotmesis), becoming the nerve recovery more rapid and efficient.

【 授权许可】

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