期刊论文详细信息
Química Nova | |
Simultaneous quantification of organic solvent biomarkers by high performance liquid chroma tography | |
Roehrs, Miguel1  Garcia, Solange Cristina1  Maria, Lucas Santa1  Limberger, Renata Pereira1  Universidade Federal de Santa Maria, Porto Alegre, Brasil1  Universidade Federal de Santa Maria, Santa Maria, Brasil1  Bulcão, Rachel1  Charão, Mariele1  Moro, Angela1  | |
关键词: HPLC; organic solvents; biological exposure index.; | |
DOI : 10.1590/S0100-40422008000600013 | |
学科分类:化学(综合) | |
来源: Sociedade Brasileira de Quimica | |
【 摘 要 】
Biological monitoring is very important to guarantee health to workers. This method was developed for simultaneous determination of xylene, toluene, styrene and ethylbenzene metabolites. It involves only dilution and centrifugation of urine samples and improved chromatographic conditions. Analyses show recovery > 95%; r2 > 0.99; intermediate precision CV% < 6% and % bias < ±10. Exposed subjects presented at least three metabolites in urine. The method proved to be feasible, reliable and important in biological monitoring, especially in exposure to organic solvent mixtures.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201912050594234ZK.pdf | 113KB | download |