A facile synthesis of 1,2,3-triazolyl indole hybrids via SbCl3-catalysed Michael addition of indoles to 1,2,3-triazolyl chalcones

Journal of Chemical Sciences

Alagusundaram Ponnuswamy1¹  Murugan Sathishkumar¹  Sangaraiah Nagarajan¹  Poovan Shanmugavelan¹ 

[1] Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai 625 021, India$$

关键词: Environmentally benign;    1;    2;    3-triazolyl chalcone;    Michael addition;    SbCl3 catalysed;    1;    2;    3-triazolyl indole.;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

An efficient, facile and environmentally benign synthesis of a library of 1,2,3-triazolyl chalcone hybrids (3a-u) has been accomplished by grinding the reactants at room temperature in excellent yields in very short reaction time. Subsequently, SbCl3 catalysed Michael addition of indoles to the chalcones afford 1,2,3-triazolyl indole hybrids (5a-l) in excellent yields.

【 授权许可】

Unknown