Presence of immunoreactive endothelin in human milk

FEBS Letters

Ghatei, Mohammed A.¹  Bloom, Stephen R.¹  Takahashi, Kazuhiro¹  Lam, Hing-Chung¹ 

[1] Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, Du Cane Road, London, W12 ONN, England

关键词: Endothelin;    Chromatography;    Human milk;    Radioimmunoassay;   

DOI  :  10.1016/0014-5793(90)80666-7

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Endothelin-like immunoreactivity was detected in human milk at a concentration of 6.8 ± 1.6 (mean ± SEM; n = 16) using a highly sensitive radioimmunoassay. Gel filtration and fast protein liquid chromatography (FPLC) verified the identity of the endothelin. FPLC revealed 4 peaks, one eluting just after the void volume, and the other three in the positions of endothelin-1, -2, and -3, respectively.

【 授权许可】

Unknown