On the presence of two new high mobility group‐like proteins in HeLa S3 cells

FEBS Letters

Lund, Terje¹  Fredriksen, Marianne¹  Holtlund, Jostein¹  Laland, Søren G.¹ 

[1] Department of Biochemistry, University of Oslo, Blindern, Oslo 3, Norway

关键词: High mobility group-like protein;    Interphase;    Metaphase;    Phosphorylation;    PMSF;    phenylmethyl sulphonyl fluoride;   

DOI  :  10.1016/0014-5793(83)80370-6

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Two phosphorylated HMG-like proteins with M _r ≈ 10 000 have been isolated from HeLa S3 cells, one being present in metaphase and one in interphase cells. The amino acid compositions of these proteins are very similar but differ from the known HMG proteins. However, they exhibit similarities being rich in proline, basic and acidic amino acids. A possible role in chromatin condensation of the HMG-like protein characteristic for metaphase cells is suggested.

【 授权许可】

Unknown