Phytochemicals and antimicrobial potentials of mahogany family

Revista Brasileira de Farmacognosia

Chiruvella, Kishore K.¹  Thammineni, Chakradhar¹  International Crop Research Institute for Semi Arid Tropics, Patancheru, IN¹  Paritala, Vikram¹  Ghanta, Rama Gopal¹  Sri Venkateswara University, Tirupati, IN¹  Universiti Malaysia Kelantan, Kelantan, MY¹  Stockholm University, SE¹  Mohammed, Arifullah¹ 

关键词: Limonoids;    Flavonoids;    Antibacterial;    Antifungal activity;   

DOI  :  10.1016/j.bjp.2014.11.009

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

Drug resistance to human infectious diseases caused by pathogens lead to premature deaths through out the world. Plants are sources for wide variety of drugs used for treating various diseases. Systematic screening of medicinal plants for the search of new antimicrobial drug candidates that can inhibit the growth of pathogens or kill with no toxicity to host is being continued by many laboratories. Here we review the phytochemical investigations and biological activities of Meliaceae. The mahogany (Meliaceae) is family of timber trees with rich source for limonoids. So far, amongst the different members of Meliaceae, Azadirachta indica and Melia dubia have been identified as the potential plant systems possessing a vast array of biologically active compounds which are chemically diverse and structurally complex. Despite biological activities on different taxa of Meliaceae have been carried out, the information of antibacterial and antifungal activity is a meager with exception to Azadirachta indica. Together we provide new insights of Meliaceae members demonstrating as a potential source as antimicrobial agents using in vitro studies.

【 授权许可】

Unknown