Arrabidaea chica (HBK) Verlot: phytochemical approach, antifungal and trypanocidal activities

Revista Brasileira de Farmacognosia

Wagner Luiz Ramos Barbosa¹  Lucianna Do Nascimento Pinto¹  Etienne Quignard¹  José Maria Dos Santos Vieira¹  José Otávio Carrera Silva Jr.¹  Sérgio Albuquerque¹ 

关键词: Arrabidaea chica;    Bignoniaceae;    Flavonoids;    Trichophyton mentagrophytes;    Antifungal activity;    Trypanosoma cruzi;    Trypanocidal effect;    Arrabidaea chica;    Bignoniaceae;    Flavonóides;    Trichophyton mentagrophytes;    Atividade antifúngica;    Trypanosoma cruzi;    Efeito tripanocida;   

DOI  :  10.1590/S0102-695X2008000400008

来源: SciELO

【 摘 要 】

Arrabidaea chica (HBK.) Verlot (Bignoniaceae) vernacular name "Pariri", is a climbing shrub, widespread from South Mexico to Guyana and central Brazil and is traditionally indicated to treat symptoms of inflammations and skin affections. Its ethanol extract was chemically investigated and tested against yeasts and dermatophytic fungi. The trypanocidal activity of the same extract was also evaluated. This work reports the isolation of three flavonoids, the total growth inhibition of Trichophyton mentagrophytes and a significant trypanocidal effect of the ethanol extract and its fractions. No relevant acute toxicity was detected even at a dose of 1000 mg/kg.

【 授权许可】

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