Arrabidaea chica (HBK) Verlot: phytochemical approach, antifungal and trypanocidal activities

Revista Brasileira de Farmacognosia

Pinto, Lucianna do Nascimento¹  Barbosa, Wagner Luiz Ramos¹  Quignard, Etienne¹  Silva Jr., José Otávio Carrera¹  Albuquerque, Sérgio¹  Vieira, José Maria dos Santos¹ 

关键词: Arrabidaea chica;    Bignoniaceae;    Flavonoids;    Trichophyton mentagrophytes;    Antifungal activity;    Trypanosoma cruzi;    Trypanocidal effect.;   

DOI  :  10.1590/S0102-695X2008000400008

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

Arrabidaea chica (HBK.) Verlot (Bignoniaceae) vernacular name "Pariri", is a climbing shrub, widespread from South Mexico to Guyana and central Brazil and is traditionally indicated to treat symptoms of inflammations and skin affections. Its ethanol extract was chemically investigated and tested against yeasts and dermatophytic fungi. The trypanocidal activity of the same extract was also evaluated. This work reports the isolation of three flavonoids, the total growth inhibition of Trichophyton mentagrophytes and a significant trypanocidal effect of the ethanol extract and its fractions. No relevant acute toxicity was detected even at a dose of 1000 mg/kg.

【 授权许可】

Unknown