Modern stationary phases for reversed phase high performance liquid chromatography

Quimica nova

Jardim, Isabel C. S. F.¹  Collins, Carol H.¹  Maldaner, Liane¹ 

[1] Universidade Estadual de Campinas, Campinas, Brasil

关键词: RP-;    HPLC;    modern stationary phases;    stability.;   

DOI  :  10.1590/S0100-40422010000700024

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

This review first discusses the limitations of many of the supports and stationary phases used in reversed phase high performance liquid chromatography and then describes those, developed more recently, that present better stabilities and more versatile selectivities. Emphases will be given to stationary phases that use higher purity silicas, hybrid silicas, monolithic silicas, metallic oxides and mixed oxides as supports and those that have embedded polar groups or contain phenyl or fluoro groups as the stationary phase as well as the phases used for mixed mode or hydrophilic interaction separations. These modern stationary phases facilitate the analysis of complex mixtures.

【 授权许可】

CC BY