An unusual case of Acanthamoeba Polyphaga and Pseudomonas Aeruginosa keratitis

Diagnostic Pathology

Xinghuai Sun³  Zuguo Liu¹  Wenjun Cao²  Jianjiang Xu²  Jian Ji²  Jiaxu Hong¹ 

[1] Eye Institute of Xiamen University, Fujian 361005, China;Department of Ophthalmology and Visual Science, Eye, Ear, Nose, and Throat Hospital, School of Shanghai Medicine, Fudan University, 83 Fenyang Road, Shanghai 200031, China;Myopia Key Laboratory of Ministry of Health, Shanghai, China

关键词: Pseudomonas aeruginosa;    Acanthamoeba species;    Contact lens;   

Others  :  801624
DOI  :  10.1186/1746-1596-9-105

 received in 2013-12-04, accepted in 2014-05-18,  发布年份 2014

【 摘 要 】

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A 56-year-old woman with a history of disposable soft contact lens wear was referred to our university eye center for a corneal ulcer. Based on the microbial culture, the initial diagnosis was bacterial keratitis, which was unresponsive to topical fortified antibiotics. The patient was then examined using in vivo confocal microscopy, which revealed Acanthamoeba infection. This case emphasizes the need to suspect Acanthamoeba infection in soft contact lens wearers who present with progressive ulcerative keratitis or progressively worsening corneal ulcers that are not responsive to the usual antimicrobial therapy. It is also important to consider the possibility of a coinfection with bacterial and Acanthamoeba species.

【 授权许可】

   
2014 Hong et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

【 参考文献 】

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