A review of functional slit lamp biomicroscopy

Eye and Vision

Xupeng Shu¹  Liang Hu¹  Jianhua Wang² 

[1] 0000 0001 0348 3990, grid.268099.c, School of Ophthalmology and Optometry, Wenzhou Medical University, 325027, Wenzhou, China;0000 0004 1936 8606, grid.26790.3a, Bascom Palmer Eye Institute, University of Miami, Miami, Florida, USA;

关键词: Functional slit lamp biomicroscopy (FSLB);    Conjunctival blood flow velocity;    Microvascular network density;    Contact lens;    Dry eye disease;   

DOI  :  10.1186/s40662-019-0140-7

来源: publisher

【 摘 要 】

Functional slit lamp biomicroscopy (FSLB) is a novel device which consists of a traditional slit-lamp and a digital camera. It can quantitatively assess vessel diameter, blood flow velocity, and blood flow rate and can create noninvasive microvascular perfusion maps (nMPMs). At present, FSLB is mainly used in contact lens (CL) and dry eye disease (DED) studies to advance our understanding of ocular surface microcirculation. FSLB-derived blood flow and vessel density measures are significantly altered in CL wearers and DED patients compared to normal people. These subtle changes in the ocular surface microcirculation may contribute to the monitoring of potential diseases of the body and provide a new way to diagnose dry eye disease. Therefore, this may also indicate that FSLB can be more widely applied in the study of other diseases to reveal the relationship between changes in ocular surface microcirculation and systemic diseases. The purpose of this paper is to summarize the functions of FSLB and the related studies especially in CL and DED.

【 授权许可】

CC BY