Feasibility of aortic valve assessment with low dose prospectively triggered adaptive systolic (PTAS) cardiac computed tomography angiography

BMC Research Notes

Brian B Ghoshhajra¹  Udo Hoffmann¹  Suhny Abbara¹  Leif-Christopher Engel¹  Manavjot S Sidhu¹  Gladwin C Hui¹  Bryan Wai¹  Wai-Ee Thai¹  Jonathan Beaudoin¹  Ashley M Lee¹ 

[1] Department of Radiology and Division of Cardiology, Cardiac MR PET CT Program, Massachusetts General Hospital and Harvard Medical School, 165 Cambridge St, Suite 400, Boston, MA, 02114, USA

关键词: Low dose;    Aortic stenosis;    Computed tomography angiography;   

Others  :  1142886
DOI  :  10.1186/1756-0500-6-158

 received in 2013-01-25, accepted in 2013-04-12,  发布年份 2013

【 摘 要 】

Background

Cardiac computed tomography angiography (CTA) is feasible for aortic valve evaluation, but retrospective gated protocols required high radiation doses for aortic valve assessment. A prospectively triggered adaptive systolic (PTAS) cardiac CT protocol was recently described in arrhythmia using second-generation dual-source CT. In this study, we sought to evaluate the feasibility of PTAS CTA to assess the aortic valve at a low radiation dose.

Findings

A retrospective cohort of 29 consecutive patients whom underwent PTAS protocols for clinical indications other than aortic valve assessment and whom also received echocardiography within 2 months of CT, was identified. Images were reviewed for aortic valve morphology (tricuspid/bicuspid/prosthetic) and stenosis (AS) by experienced blinded readers. Accuracy versus echocardiography and radiation doses were assessed.

All PTAS coronary CTAs were clinically diagnostic with 0 un-evaluable coronary segments. The accuracy of PTAS for aortic valve morphology was 92.6%, and for exclusion of severe AS was 93.1%. Two exams were un-evaluable for the aortic valve due to inadequate number of phases archived for interpretation. Total radiation dose was a median of 2.8 mSv (interquartile range 1.4–4.4 mSv).

Conclusions

PTAS CTA protocols using second-generation dual-source CT for aortic valve evaluation are feasible at low doses. This protocol should be investigated further in larger cohorts.

【 授权许可】

   
2013 Lee et al.; licensee BioMed Central Ltd.

【 图 表 】

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