Defining a Possible Low LET Bystander Effect

Charles R. Geard

关键词: Radiation Protection;    Low dose;    Low Linear Energy Transfer;    Dose Response;    Bystander Effect;   

DOI  :  10.2172/951905
RP-ID  :  DOE/ER/62687- Final Report
PID  :  OSTI ID: 951905

学科分类：核能源与工程

美国|英语

来源: SciTech Connect

【 摘 要 】

Current radiation protection guidelines assume a linear response to ionizing radiations down through doses where epidemiological studies provide very limited to no information as to the propriety of such assumptions. The bystander response is a non-targeted effect which might impact such guidelines. These studies while clearly affirming a bystander response for high LET radiations, do not provide such affirmation for environmentally relevant low dose, low LET radiations. Caution and further study are necessary before making judgements that could impact on current standards.