Defining a Possible Low LET Bystander Effect

Geard, Charles R.

Center for Radiological Research, Columbia University Medical Center, New York, NY

关键词: Bystander Effect;    61 Radiation Protection And Dosimetry Radiation Protection;    Radiation Protection;    Low Dose;    Dose Response;   

DOI  :  10.2172/951905
RP-ID  :  DOE/ER/62687- Final Report
RP-ID  :  FG02-98ER62687
RP-ID  :  951905

美国|英语

来源: UNT Digital Library

【 摘 要 】

Current radiation protection guidelines assume a linear response to ionizing radiations down through doses where epidemiological studies provide very limited to no information as to the propriety of such assumptions. The bystander response is a non-targeted effect which might impact such guidelines. These studies while clearly affirming a bystander response for high LET radiations, do not provide such affirmation for environmentally relevant low dose, low LET radiations. Caution and further study are necessary before making judgements that could impact on current standards.