Dependence of seed layer thickness on sensitivity of nano-ZnO cholesterol biosensor

1st International Conference on New Material and Chemical Industry

材料科学;化学工业

Lu, Yang-Ming^1 ; Wang, Po-Chin^1 ; Tang, Jian-Fu^2 ; Chu, Sheng-Yuan^2

Department of Electrical Engineering, National University of Tainan, Tainan, Taiwan^1

Department of Electrical Engineering, National Cheng Kung University, Tainan, Taiwan^2

关键词: Cholesterol biosensor;    Cholesterol oxidase;    High sensitivity;    Hydrothermal methods;    Nano-biosensors;    Seed layer thickness;    ZnO nanostructures;    Zno seed layers;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/167/1/012021/pdf
DOI  :  10.1088/1757-899X/167/1/012021

学科分类：材料科学（综合）

来源: IOP

【 摘 要 】

The anemone-like ZnO nanostructures have been synthesized by hydrothermal method and were further adsorbed immobilized cholesterol oxidase (ChOx) as a nano-biosensor. In this study, the sensitivity of biosensor were improved by varying the thickness of the ZnO seed layer. The SEM analysis showed changes in thickness of seed layer will not affect the morphologies of anemone-like ZnO nanostructures. The X-ray Diffraction patterns showed that the (002) plane of anemone-like ZnO grown on various thickness of the seed layer was more prouded than other crystal plane. Abioelectrode (ChOx/ZnO/ITO/glass) grown on the 30nm of ZnO seed layer with high sensitivity of 57.533μAmM-1cm-2 (1.488 μA (mg/dl) -1cm-2), a wide sensitive range from 25 to 500 mg/dl. It is concluded that the thinner sputtered ZnO seed layer for growing anemone-like ZnO nanostructure can effectively improve the sensitivity of the ZnO biosensor.