Synthesis High Sensivity ZnO Cholesterol Biosensor with One Dimensional Nanostructures

4th International Conference on Manufacturing, Optimization, Industrial and Material Engineering

Lu, Y.M.^1 ; Jhuang, P.G.^1 ; Tang, J.F.^2 ; Chu, S.Y.^2 ; Hsu, Cw^1

Department of Electrical Engineering, National University of Tainan, Taiwan^1

Department of Electrical Engineering, National Cheng Kung University, Tainan, Taiwan^2

关键词: Cholesterol biosensor;    Concentration ranges;    High sensitivity;    Hydrothermal methods;    One-dimensional nanostructure;    Seed layer;    ZnO nanostructures;    Zno seed layers;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/131/1/012004/pdf
DOI  :  10.1088/1757-899X/131/1/012004

来源: IOP

【 摘 要 】

Chelosterol ZnO biosensors were synthesized by hydrothermal method with predeposited ALD-ZnO seed layers. The ZnO nanostructures were examined by SEM, XRD, AFM, respectively. The XRD is used to analyze the crystal structures of ZnO seed layers that were grown by ALD process, then using SEM and AFM to analysis the surface morphologies of them. Growing of one dimensional ZnO nanostructures on seed layer of 10nm thickness, reveals high sensitivity of 3.15 uA (mg/dl)-1cm-2(121.96 uAmM-1cm-2) and low Kmvalue of 29mM in 25-100mg/dl cholesterol concentration range. The response time could be as low as 10seconds. In the study, it is found that increasing the aspect ratio of ZnO one dimensional nanostructure also increases the sensitivity and expends the linear measureable range of detecting cholesterol in solution. The thickness of seed layer has a significant influence on sensitivity for one dimensional nano ZnO cholesterol biosensor.