Aerosol sampling using an electrostatic precipitator integrated with a microfluidic interface

SENSORS AND ACTUATORS B-CHEMICAL

卷:212

Article

Pardon, Gaspard¹  Ladhani, Laila¹  Sandstrom, Niklas¹  Ettori, Maxime¹  Lobov, Gleb¹  van der Wijngaart, Wouter¹ 

[1] KTH Royal Inst Technol, Micro & Nanosyst, S-10044 Stockholm, Sweden

关键词: Exhaled breath analysis;    Electrostatic precipitator;    Microfluidics;    Lab-on-a-chip;    Diagnostics;    Aerosol sampling;   

DOI  :  10.1016/j.snb.2015.02.008

来源: Elsevier

【 摘 要 】

In this work, the development of a point-of-care (PoC) system to capture aerosol from litres of air directly onto a microfluidic lab-on-chip for subsequent analysis is addressed. The system involves an electrostatic precipitator that uses corona charging and electrophoretic transport to capture aerosol droplets onto a microfluidic air-to-liquid interface for downstream analysis. A theoretical study of the governing geometric and operational parameters for optimal electrostatic precipitation is presented. The fabrication of an electrostatic precipitator prototype and its experimental validation using a laboratory-generated aerosolized dye is described. Collection efficiencies were comparable to those of a state-of-the-art Biosampler impinger, with the significant advantage of providing samples that are at least 10 times more concentrated. Finally, we discuss the potential of such a system for breath-based diagnostics. (C) 2015 Elsevier B.V. All rights reserved.

【 授权许可】

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