Lab-on-a-chip for high frequency acoustic characterization

SENSORS AND ACTUATORS B-CHEMICAL

卷:177

Article

Gao, Jiaming^1,2  Carlier, Julien¹  Wang, Shengxiang³  Campistron, Pierre¹  Callens, Dorothee¹  Guo, Shishang²  Zhao, Xingzhong²  Nongaillard, Bertrand¹ 

[1] Univ Lille Nord France, UVHC, IEMN, DOAE,CNRS,UMR 8520, F-59313 Valenciennes, France

[2] Wuhan Univ, Dept Phys, Wuhan 430072, Peoples R China

[3] Wuhan Text Univ, Sch Elect & Elect Engn, Wuhan 430073, Peoples R China

关键词: Ultra high frequency transducer;    Acoustical characterization;    Lab-on-a-chip;    Microfluidics;    Bulk acoustic wave;   

DOI  :  10.1016/j.snb.2012.11.037

来源: Elsevier

【 摘 要 】

This paper presents an acoustofluidics platform for elastic characterization of biological samples using ultra high frequency (similar to 1 GHz) ultrasonic bulk acoustic waves (BAW). The propagation of bulk acoustic waves in a plane parallel to the surface of a silicon wafer was controlled using 45 degrees acoustic mirrors, thus leading to the development of real time biosensing applications in a microchannel fabricated using ICP technology. To validate the design and technology of the silicon and PDMS-based platform, the propagation of bulk acoustic waves through the microfluidic channel was studied. This lab-on-a-chip platform was used to characterize different concentrations of chemical solutions in the microfluidic channel and detect latex particles passing through the channel. (c) 2012 Elsevier B.V. All rights reserved.

【 授权许可】

Free