Six-month changes in ideal cardiovascular health vs. Framingham 10-year coronary heart disease risk among young adults enrolled in a weight loss intervention

PREVENTIVE MEDICINE

卷:86

Article

Gibbs, Bethany Barone¹  King, Wendy C.²  Belle, Steven H.²  Jakicic, John M.¹ 

[1] Univ Pittsburgh, Dept Hlth & Phys Act, Pittsburgh, PA 15260 USA

[2] Univ Pittsburgh, Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA 15260 USA

关键词: Prevention;    Lifestyle;    Obesity;    Risk factors;    Young adults;    Cardiovascular health;   

DOI  :  10.1016/j.ypmed.2016.02.033

来源: Elsevier

【 摘 要 】

The Framingham Risk equation uses sex, age, smoking, total cholesterol, high-density lipoprotein (HDL) cholesterol and systolic blood pressure to predict 10-year risk of coronary heart disease (FR-10). The American Heart Association's Ideal Cardiovascular Health (IDEAL) score uses smoking, total cholesterol, fasting glucose, blood pressure, body mass index (BMI), diet, and physical activity to encourage a healthy cardiovascular phenotype. This study aimed to compare 6-month changes in the FR-10 vs. IDEAL score among young adults with BMI >= 25 to <40 kg/m(2) enrolled in a behavioral weight loss intervention at the University of Pittsburgh (2010-12). Medians [25th, 75th percentiles] are reported. Weight decreased by 8 kg [-12, -4] among 335 participants. Of 7 possible points, IDEAL score was 4 [3, 4] at baseline, improved (i.e., increased) by 1 [0, 2] over 6 months, and improved in 64.2% and worsened in 6.6% of participants (p < 0.001). IDEAL classification of BMI, physical activity, total cholesterol, blood pressure and glucose improved (all p < 0.001), but not of smoking or diet (both p >= 0.05). FR-10 was <1% at baseline for 88.1% of participants and changed in few participants (improved, i.e. decreased, in 7.5%, worsened in 1.8%, p < 0.001). Among young adults with overweight or obesity enrolled in a weight loss intervention, IDEAL detected positive changes in a majority of participants while the FR-10 did not. These findings suggest that IDEAL score may be more sensitive to positive cardiovascular health changes resulting from a behavioral intervention in this population. (C) 2016 Elsevier Inc. All rights reserved.

【 授权许可】

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