Two novel tetracycles, cassibiphenols A and B from the flowers of Cassia siamea

TETRAHEDRON LETTERS

卷:55

Article

Deguchi, Jun¹  Sasaki, Tadahiro¹  Hirasawa, Yusuke¹  Kaneda, Toshio¹  Kusumawati, Idha²  Shirota, Osamu³  Morita, Hiroshi¹ 

[1] Hoshi Univ, Fac Pharmaceut Sci, Shinagawa Ku, Tokyo 1428501, Japan

[2] Airlangga Univ, Fac Pharm, Surabaya 60286, Indonesia

[3] Tokushima Bunri Univ, Fac Pharmaceut Sci, Sanuki City, Kagawa 7692193, Japan

关键词: Cassia siamea;    Cassibiphenols A and B;    Biphenyl;    Structure elucidation;    Partial synthesis;   

DOI  :  10.1016/j.tetlet.2014.01.023

来源: Elsevier

【 摘 要 】

Chemical investigation of the flowers of Cassia siamea (Leguminosae), resulted in the isolation of two novel tetracycles connecting 5-(2-hydroxypropyl)benzene-1,3-diol, cassibiphenols A (1) and B (2). The structures were elucidated by analysis of the 1D, 2D NMR, and HRMS spectra. Synthesis of a tetracyclic core of 1 and 2 led to determine the absolute configuration of I and C-12 of 2. (C) 2014 Elsevier Ltd. All rights reserved.

【 授权许可】

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