Isoflavanones from the Stem of Cassia siamea and Their Anti-tobacco Mosaic Virus Activities

Bulletin of the Korean chemical society

Yan-Qing Ye¹  Xue-Mei Gao¹  Bin Zhou¹  Gang Du¹  De-Yun Niu¹  Chun-Yang Meng¹  Qiu-Fen Hu¹ 

关键词: Cassia siamea;    Isoflavanones;    Anti-tobacco mosaic virus activity;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

Two new isoflavanones, (3R) 7,2`,4`-trihydroxy-3`-methoxy-5-methoxycarbonyl-isoflavanone (1) and (3R) 7,2`-dihydroxy-3`,4`-dimethoxy-5-methoxycarbonyl-isoflavanone (2), together with six known isoflavanones (3-8), were isolated from the stems of Cassia siamea. The structure of 1-8 was elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques. Compounds 1, 2, 5-8 were evaluated for their antitobacco mosaic virus (Anti-TMV) activity. The results showed that compounds 1 and 6 showed potential anti- TMV activity with inhibition rates of 24.6% and 26.9%, respectively. Compounds 2, 5, 7, 8 also showed anti- TMV activity with inhibition rates in the range of 11.8-18.6%.

【 授权许可】

Unknown