The prevalence of ESBL-producing Enterobacteriaceae in a nursing home setting compared with elderly living at home: a cross-sectional comparison

BMC Infectious Diseases

Research Article

Fredrik Månsson¹  Jonas Ahl¹  Johan Tham¹  Andreas Blom¹  Fredrik Resman¹ 

[1] Infectious Diseases Research Unit, Deptment of Clinical sciences, Lund University, Skånes University hospital, 205 02, Malmö, Sweden;

关键词: Elderly;    ESBL;    Nursing home;    Enterobacteriaceae;   

DOI  :  10.1186/s12879-016-1430-5

 received in 2015-06-03, accepted in 2016-02-11,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundThe aim of the study was to investigate the prevalence of faecal carriage of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae among residents living in nursing homes and to compare it with a corresponding group of elderly people living in their own homes.MethodsA total of 160 persons participated in the study between February and April 2014, 91 were residents in nursing homes (n = 10) and the remaining 69 were elderly living in their own homes. In addition to performing faecal samples, all participants answered a standardized questionnaire regarding known risk factors for ESBL-carriage.ResultsThere was no significant difference between the groups, as 10 of the 91 (11 %) residents from nursing homes were ESBL-carriers compared with 6 of 69 (8,7 %) elderly living in their own homes. There was no significant difference between the groups. The total prevalence was 10 %. A univariate analysis revealed that the only studied risk factor significantly associated with ESBL-carriage was recent foreign travel (p = 0,017). All ESBL-positive isolates were Escherichia coli and there was a high degree of co-resistance to other antibiotics. All isolates (n = 17) were susceptible to imipenem and amikacin.ConclusionResidents of nursing homes as well as elderly living in their own homes have high rates of faecal carriage of ESBL-producing bacteria. These findings may affect the choice of empirical antibiotic treatment of severe infections in older adults.

【 授权许可】

CC BY   
© Blom et al. 2016