Evaluation of antibiotic resistance of Enterobacteriaceae bacteria isolated from water objects of the north-west of the Murmansk region

Arctic Biomonitoring

Zatsarinnaya, E.A.^1 ; Efremova, E.S.^2 ; Gas'Kova, A.S.^1 ; Kolupaeva, L.V.^1 ; Trunyakova, A.S.^3

Scientific Laboratory of Evolutionary Ecology, Ryazan State University Named by S. A. Esenin, Svobody st 46, Ryazan

390000, Russia^1

Department of Management and Economics of Pharmacy, Ryazan State Medical University Named after Academicial I.P. Pavlov, Vysokovoltnaya st 9, Ryazan

390026, Russia^2

Laboratory for Plague Microbiology, State Research Center for Applied Microbiology and Biotechnology, Moscow region Obolensk

142279, Russia^3

关键词: Antibiotic resistance;    Antimicrobial resistances;    Antimicrobial susceptibility;    Citrobacter freundii;    Enterobacteria;    Enterobacteriaceae;    Multidrug resistance;    Water environments;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/263/1/012035/pdf
DOI  :  10.1088/1755-1315/263/1/012035

来源: IOP

【 摘 要 】

Multidrug antimicrobial resistance among different species of the family Enterobacteriaceae remains a major problem worldwide. In this paper, we report the data on antimicrobial susceptibility of 145 isolates of Enterobacteriaceae collected in 14 water environments of the north-west of the Murmansk region in autumn 2016. The number of Enterobacteriaceae in the examined rivers was rather low. Only the concentration of enterobacteria exceed the regulations in water samples from lake Kuetsjarvi. The detected isolates were assigned to eight species of enterobacteria. The most abundant species were Enterobacter spp. (26.9%) and Citrobacter freundii (25.3%). Isolates of Escherichia coli were not detected. Most of the isolates (96.6%) were multi-drug resistance (MDR). Notably, 16.6% of the all isolates were categorized as possible extensively drug-resistant (XDR). Almost all isolates were showing high level resistance to β-lactams, especially to cefepime and imipenem. Most effective antimicrobial agent were tobramycin and norfloxacin.