Comparative analysis of pulmonary and extrapulmonary tuberculosis of 411 cases

Annals of Clinical Microbiology and Antimicrobials

Research

Irfan Binici¹  Aysel Sunnetcioglu²  Ali Irfan Baran³  Mustafa Kasım Karahocagil³  Mahmut Sunnetcioglu³  Muhammed Rıdvan Saydan⁴ 

[1] Department of Clinical Bacteriology and Infectious Disease, Ercis State Hospital, Van, Turkey;Department of Pulmonary, Yuzuncu Yil University Medical Faculty, Van, Turkey;Medical Faculty, Department of Clinical Bacteriology and Infectious Diseases, Yuzuncu Yil University, Van, Turkey;Tuberculosis Control Dispensary, Van, Turkey;

关键词: Tuberculosis;    Pulmonary;    Extrapulmonary;    Epidemiology;   

DOI  :  10.1186/s12941-015-0092-2

 received in 2015-03-16, accepted in 2015-06-15,  发布年份 2015

来源: Springer

【 摘 要 】

BackgroundTuberculosis is a disease that can involve every organ system. While pulmonary tuberculosis is the most common presentation, extrapulmonary tuberculosis (EPT) is also an important clinical problem. The current study aimed to outline and compare the demographic and clinical features of pulmonary and extrapulmonary tuberculosis cases in adults.MethodsMedical records of 411 patients (190 women, 221 men) treated between January 2010 and July 2014 in provincial tuberculosis control dispensary was retrospectively reviewed. Demographic and clinical characteristics were compared for pulmonary and extrapulmonary tuberculosis cases.ResultsOf these 411 cases, 208 (50.6 %) had pulmonary tuberculosis (PTB) and 203 were diagnosed with extrapulmonary tuberculosis (EPTB) (49.4 %). The average ages for PTB and EPTB groups were 33.00-27.00 and 31.00-29.75, respectively (p = 0.513). Men were more frequently affected by PTB (59.6 %), while EPTB was more commonly detected in women (52.2 %) (p = 0.016). Main diagnostic modalities for PTB were sputum/smear analyses (72.7 %), clinical-radiological data (21.7 %) and biopsy (6.1 %); while biopsy (71.5 %), sputum/fluid analysis (18.8 %) and clinical-radiological data (4.9 %) were used for confirming EPTB (p < 0.0019). The most common sites of EPTB involvement were lymph nodes (39.4 %), followed by pleura (23.6 %), peritoneum (9.9 %) and bone (7.4 %).ConclusıonsExtrapulmonary involvement of tuberculosis is common and females are more likely to be affected. Increased clinical awareness is important since atypical presentations of the disease may constitute diagnostic and therapeutic challenges.

【 授权许可】

CC BY   
© Sunnetcioglu et al. 2015