The prevalence of polycystic ovary syndrome in a community sample of Iranian population: Iranian PCOS prevalence study

Reproductive Biology and Endocrinology

Research

Farhad Hosseinpanah¹  Maryam Tohidi²  Fereidoun Azizi²  Masoumeh Simbar²  Fahimeh Ramezani Tehrani² 

[1] Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran;Reproductive Endocrinology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran;

关键词: Polycystic Ovary Syndrome;    Congenital Adrenal Hyperplasia;    Hyperandrogenism;    Free Androgen Index;    Idiopathic Hirsutism;   

DOI  :  10.1186/1477-7827-9-39

 received in 2011-01-08, accepted in 2011-03-25,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundDespite the heavy burden and impact of the polycystic ovary syndrome (PCOS) in reproduction and public health, estimates regarding its prevalence at community levels are limited. We aimed to ascertain prevalence of PCOS in a community based sample using the National Institute of Health (NIH), the Rotterdam consensus (Rott.) and the Androgen Excess Society (AES) criteria.MethodsUsing the stratified, multistage probability cluster sampling method, 1126 women were randomly selected from among reproductive aged women of different geographic regions of Iran. PCOS were diagnosed using universal assessment of ultrasonographic parameters, hormonal profiles and clinical histories.ResultsThe mean +/- SD of age of study population was 34.4 +/- 7.6 years. Estimated prevalence of idiopathic hirsutism was 10.9% (95% CI: 8.9-12.9%); 8.3% of women had only oligo/anovulation and 8.0% had only polycystic ovaries. The prevalence of PCOS was 7.1% (95% CI: 5.4-8.8%) using the NIH definition, 11.7% (95% CI: 9.5-13.7%) by AES criteria and 14.6% (95% CI: 12.3-16.9%) using the Rott definition.ConclusionsAt community level, widespread screening of Rotterdam criteria will increase the estimated prevalence of PCOS over twofold. Establishing an explicit and contemporaneous method for definition and screening of each PCOS criteria has important investigational implications and increase the comparability of published research.

【 授权许可】

CC BY   
© Tehrani et al; licensee BioMed Central Ltd. 2011