The combination matters - distinct impact of lifestyle factors on sperm quality: a study on semen analysis of 1683 patients according to MSOME criteria

Reproductive Biology and Endocrinology

Research

Anton Neyer¹  Maximilian Schuff¹  Barbara Wirleitner¹  Birgit Schechinger¹  Astrid Stecher¹  Nicolas H Zech¹  Johannes Wogatzky¹  Pierre Vanderzwalmen²  Dietmar Spitzer³ 

[1] IVF Centers Prof Zech-Bregenz, Roemerstrasse 2, 6900, Bregenz, Austria;IVF Centers Prof Zech-Bregenz, Roemerstrasse 2, 6900, Bregenz, Austria;Centre Hospitalier Inter Régional Cavell (CHIREC), 1420 Braine-l‘alleud, Brussels, Belgium;IVF Centers Prof Zech-Salzburg, Innsbrucker Bundesstr. 35, 5020, Salzburga, Austria;

关键词: Sperm quality;    MSOME;    IMSI;    Lifestyle;    BMI;    Ejaculation frequency;    Oxidative stress;   

DOI  :  10.1186/1477-7827-10-115

 received in 2012-10-08, accepted in 2012-12-12,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundPoor sperm quality can negatively affect embryonic development and IVF outcome. This study is aimed at investigating the influence of various lifestyle factors on semen quality according to MSOME (motile sperm organelle morphology examination) criteria.Methods1683 male patients undergoing assisted reproductive technologies (ART) in our clinic were surveyed about their age, BMI (body mass index), ejaculation frequency, nutrition, sports, sleeping habits and social behavior. Semen samples were collected and evaluation of semen parameters according to MSOME and WHO criteria was performed. Results were grouped and statistically analyzed.ResultsAlthough single parameters had minor effects on sperm parameter, the combination of age, BMI, coffee intake, ejaculatory frequency and duration of sexual abstinence were identified as factors having a negative effect on sperm motility. Additionally, we could demonstrate that MSOME quality was reduced. The negative impact of age, BMI and coffee intake on sperm quality could be compensated if patients had a high ejaculation frequency and shorter periods of sexual abstinence.ConclusionsCombinations of adverse lifestyle factors could have a detrimental impact on sperm, not only in terms of motility and sperm count but also in terms of sperm head vacuolization. This negative impact was shown to be compensated by higher ejaculation frequency and a shorter period of sexual abstinence. The compensation is most likely due to a shorter storage time in the male gonads, thus reducing the duration of sperms’ exposure to reactive oxygen species (ROS).

【 授权许可】

CC BY   
© Wogatzky et al.; licensee BioMed Central Ltd. 2012