Seroprevalence and risk factors of Toxoplasma gondii infection in pregnant women from Bobo Dioulasso, Burkina Faso

BMC Infectious Diseases

Research Article

Robert T. Guiguemdé¹  Adama Zida¹  Souleymane Ouattara²  Ibrahim Sangaré²  Sanata Bamba²  Mamoudou Cissé² 

[1] Université Ouaga 1 Joseph-KI Zerbo, Ouagadougou, Burkina Faso;Université polytechnique de Bobo-Dioulasso, 01 BP 390, Centre MURAZ, Bobo-Dioulasso, Burkina Faso;

关键词: Toxoplasma gondii;    Seroprevalence;    Pregnant women;    Risk factors;    Burkina Faso;   

DOI  :  10.1186/s12879-017-2583-6

 received in 2017-01-21, accepted in 2017-06-30,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundToxoplasmosis is one of the common worldwide parasitic zoonosis due to Toxoplasma gondii (T. gondii). Toxoplasmosis during pregnancy can result in fetal and neonatal death or various congenital defects. The aim of this study was to assess the seroprevalence and risk factors of T. gondii infection in pregnant women following antenatal care (ANC) services at Bobo Dioulasso.MethodsA cross-sectional study was conducted enrolling a sample of 316 pregnant women attending ANC at centers for maternal and child health of Bobo-Dioulasso town from March 2013 to February 2014. Data on socio-demographic and potential risk factors were collected from each study participant using structured questionnaire through face-to-face interview. Moreover, venous blood specimens were collected and tested for IgM and IgG anti-T. gondii antibodies by enzyme-linked immunosorbent assay and enzyme linked fluorescent assay, respectively. Multivariable logistic regression modeling was used to identify the potential predictor variables for T. gondii infection.ResultsThe overall seroprevalence for T. gondii infection was 31.1% (98/316). All the pregnant women were positive for IgG anti-bodies exclusively. Multivariable logistic regression analysis showed that having at least a secondary education level (AOR = 2.23; 95% CI: [1.04–4.63]); being urban resident (AOR = 2.81; 95% CI: [1.24–6.86]) and the consumption of meat combination (pork + beef + mutton + wild meat + poultry) (AOR = 4.00; 95% CI: [1.06–15.24]) were potential risk factors of T. gondii infection.ConclusionToxoplasmosis is frequent in pregnant women and studies that show incidence of T. gondii among the neonates have to be done to introduce routine antenatal screening program to control congenital toxoplasmosis. There is the need for preventive measures such as education of pregnant women about the transmission routes and prevention methods of toxoplasmosis at ANC clinics.

【 授权许可】

CC BY   
© The Author(s). 2017