Breast Cancer and Personal Environmental Risk Factors in Marin County - Pilot Study.
Erdmann, C. A. ; Farren, G. ; Baltzell, K. ; Chew, T. ; Clarkson, C. ; Fleshman, R. ; Leary, C. ; Mizroch, M. ; Orenstein, F. ; Russell, M. L. ; Souders-Mason, V. ; Wrensch, M.
The purpose of the Personal Environmental Risk Factor Study (PERFS) pilot project was to develop methodologies and a questionnaire for a future population-based case-control study to investigate the role of selected environmental exposures in breast cancer development. Identification of etiologically relevant exposures during a period of potential vulnerability proximate to disease onset offers the possibility of clinical disease prevention even when disease initiation may have already occurred many years earlier. Certain personal environmental agents or combinations of agents may influence disease promotion. Therefore, this pilot study focused on exposures that occurred during the ten-year period prior to diagnosis for cases and the last ten years for controls, rather than more historic exposures.