期刊论文

【摘要】

Microglia are resident macrophages in the central nervous system (CNS) that play various roles during brain development and in the pathogenesis of CNS diseases. Recently, reprogramming of cellular energetic metabolism in microglia has drawn attention as a crucial mechanism for diversification of microglial functionality. Lipids are highly diverse materials and crucial components of cell membranes in every cell. Accumulating evidence has shown that lipid and its metabolism are tightly involved in microglial biology. In this review, we summarize the current knowledge about microglial lipid metabolism in health and disease.

【授权许可】

CC BY
© The Author(s) 2023

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Fig. 1

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Inflammation and Regeneration
Lipid in microglial biology — from material to mediator
Review
Shota Yamamoto¹ Takahiro Masuda¹
[1] Division of Molecular Neuroimmunology, Medical Institute of Bioregulation, Kyushu University, 812-8582, Fukuoka, Japan;
关键词: CNS; Lipid; Macrophage; Microglia;
DOI : 10.1186/s41232-023-00289-z
received in 2023-05-10, accepted in 2023-07-06, 发布年份 2023
来源: Springer
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【 参考文献 】

【摘要】

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