Advances in the application of Mxene nanoparticles in wound healing

Journal of Biological Engineering

Review

Yuan Cao¹  Guoming Liu¹  Chengdong Zhang¹  Chengzhi Liang¹  Yanling Hu¹  Zhiping Qi²  Jing He³  Chuan Fu⁴ 

[1] Department of Orthopedic Surgery, The Affiliated Hospital of Qingdao University, 266000, Shandong, PR China;Department of Orthopedic Surgery, The Second Hospital of Jilin University, 130041, Chuangchun, China;Department of Pediatric Surgery, The Affiliated Hospital of Qingdao University, 266000, Shandong, PR China;Key Laboratory of Molecular Medicine and Biotherapy in the Ministry of Industry and Information Technology, Department of Biology, School of Life Science, Beijing Institute of Technology, 100081, Beijing, PR China;

关键词: MXene;    Wound dressing;    Nanoparticles;    Wound healing;   

DOI  :  10.1186/s13036-023-00355-7

 received in 2022-08-08, accepted in 2023-05-15,  发布年份 2023

来源: Springer

【 摘 要 】

Skin is the largest organ of the human body. It plays a vital role as the body’s first barrier: stopping chemical, radiological damage and microbial invasion. The importance of skin to the human body can never be overstated. Delayed wound healing after a skin injury has become a huge challenge in healthcare. In some situations, this can have very serious and even life-threatening effects on people’s health. Various wound dressings have been developed to promote quicker wound healing, including hydrogels, gelatin sponges, films, and bandages, all work to prevent the invasion of microbial pathogens. Some of them are also packed with bioactive agents, such as antibiotics, nanoparticles, and growth factors, that help to improve the performance of the dressing it is added to. Recently, bioactive nanoparticles as the bioactive agent have become widely used in wound dressings. Among these, functional inorganic nanoparticles are favored due to their ability to effectively improve the tissue-repairing properties of biomaterials. MXene nanoparticles have attracted the interest of scholars due to their unique properties of electrical conductivity, hydrophilicity, antibacterial properties, and biocompatibility. The potential for its application is very promising as an effective functional component of wound dressings. In this paper, we will review MXene nanoparticles in skin injury repair, particularly its synthesis method, functional properties, biocompatibility, and application.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

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