The Effectiveness of Ointment of Patah Tulang Stem's (Euphorbia Tirucalli) Ethanol Extract for Burn Wound Healing on White Rats (Rattus Norvegicus)

2nd Annual Applied Science and Engineering Conference

工业技术;自然科学

Aisah, S.^1 ; Utami, P.I.^1 ; Genatrika, E.^1

Faculty of Pharmacy, Universitas Muhammadiyah Purwokerto, Indonesia^1

关键词: Ethanol extract;    Kruskal-Wallis tests;    Traditional medicines;    Wound healing;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/288/1/012055/pdf
DOI  :  10.1088/1757-899X/288/1/012055

来源: IOP

【 摘 要 】

Plants of patah tulang (Euphorbia tirucalli) is one of the plants that has been widely known by the public for a long time and is used as a traditional medicine, one of them as a wound medicine. Plants of patah tulang contains saponins, tannins and flavonoids that may help in wound healing. This study aimed to determine the effect of ointment of patah tulang stem's ethanol extract with various concentration (5%,10%,20%) for burn wound healing on white rats. Long of burn wound healing was determined by the percentage of burn wound healing obtained from the average of burn wound diameter on white rats in 26 days was observed. The data of burn wound healing percentage was analyzed with Kruskal-Wallis Test. The results showed that ointment with 20% extract concentration had the same effect as positive control in burn wound healing on white rats (p>0,05).