Nanocrystal cellulose as drug excipient in transdermal patch for wound healing: an overview

3rd International Conference on Chemical Engineering Sciences and Applications 2017

Mohd Zuki, S.A.^1 ; Abd Rahman, N.^1 ; Abu Bakar, N.F.^1

Faculty of Chemical Engineering, Universiti Teknologi MARA, Selangor, Shah Alam

40450, Malaysia^1

关键词: Controlled drug release;    Drug delivery system;    Large surface area;    Non-toxic;    Transdermal patches;    Wound healing;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/334/1/012046/pdf
DOI  :  10.1088/1757-899X/334/1/012046

来源: IOP

【 摘 要 】

Wound must be carefully treated to avoid serious infection that needs costly treatment. Method to enhance the recovery of the wound is crucial to have effective wound treatment. One of the technologies in wound treatment is transdermal patch that has the benefits of being non-invasive, easy to handle and permits constant drug dosage. In order to obtain a good controlled drug release, drug excipient needs to be investigated. Recently, natural Nanocrystal Cellulose (NCC) which can be synthesized from animal, algae, microorganism or plant has been actively used in drug delivery system as excipient. The application of NCC is advantageous due to its large surface area, biodegradable, non-toxic and abundance source.