Evaluation of clinical effects of a multidisciplinary-collaborated cancer support team for gastrointestinal cancer chemotherapy: prospective observational study protocol of M-CAST study

BMC Gastroenterology

Study Protocol

Tomoe Honda¹  Hitomi Togashi¹  Yasuo Matsubara²  Yukari Tsuru³  Mitsuko Nakazawa³  Eiko Yoshii³  Tomoko Sato³  Keisuke Baba⁴  Narikazu Boku⁴  Naoki Furukawa⁵  Yohei Iimura⁵  Masaaki Ishibashi⁵  Seiichiro Kuroda⁵  Chieko Sasuga⁵  Ayako Kamisato⁶ 

[1] Department of Clinical Nutrition, The IMSUT Hospital, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, 108-8639, Minato-Ku, Tokyo, Japan;Department of Clinical Nutrition, The IMSUT Hospital, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, 108-8639, Minato-Ku, Tokyo, Japan;Department of Oncology and General Medicine, The Institute of Medical Science Hospital, The University of Tokyo, 4-6-1, Shirokanedai, 108-8639, Minato-Ku, Tokyo, Japan;Department of Nursing, The IMSUT Hospital, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, 108-8639, Minato-Ku, Tokyo, Japan;Department of Oncology and General Medicine, The Institute of Medical Science Hospital, The University of Tokyo, 4-6-1, Shirokanedai, 108-8639, Minato-Ku, Tokyo, Japan;Department of Pharmacy, The IMSUT Hospital, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, 108-8639, Minato-Ku, Tokyo, Japan;Division of Bioethics, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, 108-8639, Minato-Ku, Tokyo, Japan;

关键词: Multidisciplinary-collaborated team;    Gastrointestinal cancer;    Chemotherapy;    Supportive care;   

DOI  :  10.1186/s12876-023-02849-6

 received in 2023-01-30, accepted in 2023-06-08,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundAlthough the multidisciplinary-collaborated team approach in cancer treatment has recently become popular, prospectively evaluated evidence is limited. We started a multidisciplinary-collaborated cancer support team (MCST) to facilitate cooperation across multidisciplinary medical staff in our hospital and established clinical evidence of supportive care. This study aimed to prospectively evaluate the clinical activity and effect of MCST in patients with gastrointestinal cancer receiving chemotherapy.MethodsThis is a single-center, single-arm, observational study. Patients with gastrointestinal cancer scheduled to receive chemotherapy are enrolled and supported by the MCST. The primary endpoints are the number of interventions by medical staff and the number of patients who showed improvement in side effects. The secondary endpoints are the severity of side effects, medical expenses, number of consultations, the acceptance rate of prescription recommendations, adjuvant chemotherapy completion rates, dose intensity, and time required for co-medical intervention. In addition, medical staff and attending physicians evaluate all adverse events.DiscussionThis study is expected to contribute to establishing new cancer-supportive care teams for patients with gastrointestinal cancer receiving chemotherapy and those with cancer receiving chemotherapy.Trial registrationThis trial was registered in the Japan Registry of Clinical Trials (jRCT) as jRCT1030220495.The date of first registration, 29/11/2022, https://jrct.niph.go.jp/search

【 授权许可】

CC BY   
© The Author(s) 2023

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