Efficacy and safety of nab-paclitaxel in combination with gemcitabine for metastatic pancreatic cancer

Metastatic pancreatic cancer;Chemotherapy;Outcome;Gemcitabine;Nab-paclitaxel;610

의과대학 의학과 ;

University:서울대학교 대학원

关键词: Metastatic pancreatic cancer;    Chemotherapy;    Outcome;    Gemcitabine;    Nab-paclitaxel;    610;   

Others  :  http://s-space.snu.ac.kr/bitstream/10371/142327/1/000000151200.pdf

美国|英语

来源: Seoul National University Open Repository

【 摘 要 】

neutropenia in 41 patients (40.6%), anemia in 23 patients (22.8%) and peripheral neuropathy in 15 patients (14.9%). Febrile neutropenia occurred in 6 patients (5.9%) during follow-up.Conclusions: Combination chemotherapy of gemcitabine and nab-paclitaxel for patients with MPC showed significant survival advantage and is a reasonable choice in palliative setting. However, careful attention for development of hematologic adverse events and severe peripheral neuropathy is required.