Gut Microbiota and Neuropsychiatric Disorders

Basic and Clinical Neuroscience

article

Reza Bidaki¹  Seyed Hossein Hekmati Moghaddam²  Maryam Sadeh³ 

[1]Research Center of Addiction and Behavioral Sciences, Diabetes Research Center, Shahid Sadoughi University of Medical Sciences

[2]Department of Advanced Medical Sciences and Technologies, School of Paramedicine, Shahid Sadoughi University of Medical Sciences

[3]Department of Laboratory Sciences, School of Paramedicine, Shahid Sadoughi University of Medical Sciences

关键词: Alzheimer's disease;    Autism spectrum disorder;    Brain-gut axis;    Microbiota;    Nervous system diseases;    Parkinson disease;   

DOI  :  10.32598/bcn.2021.3220.1

来源: Iran University of Medical Sciences

【 摘 要 】

Numerous studies in humans and animals hypothesize that gut microbiota dysbiosis is involved in the development of behavioral and neurological diseases such as depression, autism spectrum disorder, Parkinson disease, multiple sclerosis, stroke and Alzheimer's disease. Some of the most salient works so far regarding the brain-gut axis are mentioned below. The current knowledge on the impact of gut microbiota on nervous system diseases is far from being directly used for pharmacologic or nutritional advice toward restoration of normal bodily functions. It seems that a more comprehensive approach should be followed so that the individual effect of each kind of intervention on the patient’s somatic or psychological status is determined. Future research must address global need for regimens which could re-establish normal composition of gut microorganisms after each neuropsychological disorder.

【 授权许可】

Unknown