Bacteriological profile and antibiotics used for septic patients in Karbala, Iraq

Medical Journal of Babylon

article

Rana Majeed Hameed¹  Jabbar F M Alafloogee²  Ghalib K Ma’an² 

[1] Department of Biochemistry, College of Medicine, University of Kerbala;Department of Internal Medicine

关键词: Antibiotics;    bacterial profile;    methicillin-resistant Staphylococcus aureus;    sepsis;    vancomycin-resistant Staphylococcus aureus;   

DOI  :  10.4103/MJBL.MJBL_93_20

学科分类：社会科学、人文和艺术（综合）

来源: Wolters Kluwer Medknow Publications

【 摘 要 】

Background: Sepsis is an issue of globular health care, characterized by complete inflammation of the body in response to microbial infection, which results in organ malfunction. This becomes a chronic patient complication. Therefore, sepsis may be a diverse and combined disease with varying etiology, severity, and treatment plan. Objectives: The purpose of this study was to demonstrate the existence of exposure and the resistance of microorganisms to the range of antibiotics in subjects of the local community. Results: Among 11 species of bacteria isolated from a variety of specimens, Escherichia coli (22.1%) and Staphylococcus aureus (20.3%) were the most common organism found over the subjects had been collected. The most sensitive antibiotics for Gram-negative E. coli were colistin 97%, imipenem 89%, meropenem 88%, and amikacin 79%, while the highest resistant rate was benzylpenicillin 93%, and oxacillin 86%. Methicillin-resistant S. aureus (MRSA) prevalence was 90%, vancomycin-resistant S. aureus (VRSA) 31%. Conclusion: Because of the high incidence of VRSA and MRSA, clinicians should become more vigilant in using vancomycin and another important antibiotic. Moreover, maintain this useful drug to be used for a prolonged time with good efficacy.

【 授权许可】

CC BY-NC-SA